The Neanderthals became extinct because could not smoke.
American scientists reported that one of the reason for the extinction of Neanderthals as a species was that they could not smoke.
As the message of the scientists in those days, the Smoking process had not yet been mastered, however, the ancestors of humans and Neanderthals have often inhaled smoke, because they were around the campfire. But if humans have adapted to smoke inhalation, the Neanderthals could not, that is their undoing.
Neanderthals do not possess the evolutionary mechanisms that led to the emergence of a number of diseases because of the harmful effects of smoke.
The reason why ancestors of humans have adapted, became one mutation in the genome of Homo sapiens, which allowed harmless to inhale the combustion products, containing dioxins, and polycyclic aromatic hydrocarbons.