Single dose bio-engineered gel that can replace the full course of antibiotics from a common ear infection in children.
These conclusions were made by the developers of the drug from the United States.
Middle ear infection, or otitis media, usually caused by bacteria or viruses. Common symptoms include ear pain and fever, and in some cases, infection can cause fluid drainage from the ear or cause hearing loss. Although most ear infections go away on their own, some of them require the intervention of antibiotics.
To cure an ear infection that required high doses of oral antibiotics that usually lead to such side effects as diarrhea, rash, and stomatitis.
However, with the gel, the doctor can use the drug only where it is needed,” said one of the developers of drugs. The drug should be Squirting into the ear canal, where the gel hardens quickly and remains in place. A small dose of the antibiotic gradually fall into the middle ear through the eardrum. Previously, the tympanic membrane was impermeable barrier, but bioengineered gel holds the medicine past it with the help of chemical permeability enhancers (CPE). CPE is embedded in the membrane, opening the molecular pores that allow antibiotics to penetrate the outer layer of the eardrum.
The developers came to the conclusion that with the help of gel, an antibiotic has become easier to treat infection of the middle ear, especially in children, which is harmful large doses of antibiotics.
