Natural compound has slowed aging in healthy mice.
An international team of biologists have discovered a natural compound that slowed aging in healthy mice. Devoted to a study published in the journal Cell Metabolism.
In the new work scientists were able to use NMN nucleotide involved in energy metabolism of the cell, for synthesis in the animal organism of the coenzyme NAD. Directly to enter the latest stuff animals impossible.
Connection NAD is involved in the absorption of fats and carbohydrates, but its synthesis due to DNA damage with age, slowing. In particular, the coenzyme prevents weight gain, loss of insulin sensitivity and reduction in physical activity.
“We have demonstrated a way to slow down the physiological decline that occurs in aging mice, said study co-author Shin-Ichiro Imai. — This means that in aged mice is achieved at about the same level of metabolism and energy, and in young animals”.
Experiments on mice have shown that water-soluble NMN absorbed into blood within three minutes. Experts note that the reception NMN young mice has no significant effect.
Scientists believe that, as in humans, metabolism proceeds similar to mice, findings in the new study, just and for the people. Japan has already begun testing drugs with NMN on the person. This compound, as the researchers note, is contained in a number of foods, particularly broccoli, cabbage, cucumbers and avocado.
In August it was reported that doctors at the University of Pennsylvania (USA) for the first time proved the effectiveness of NAD and drugs based on its precursors in the prevention of muscle degradation. These compounds are currently popular among those engaged in physical culture and sports people.
