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The first woman that changed their genes to never grow old

 Первая женщина, изменившая свои гены, чтобы никогда не стареть

In the photo, 9 months ago Liz Parrish tested the experimental therapy, she is now 45 years

Liz Parrish explained and demonstrated to the correspondent of “KP” as he changed her body.

We will remind: in the autumn of last year for the whole world occurred first in the history of humanity’s Grand experiment. American researcher Elizabeth Parrish decided on unknown people (though not often successfully tested on animals) gene therapy. Brave ispytatelnyi introduced genetic material, which must penetrate into the cell nucleus and start the change that stops aging and rejuvenating the body.

Now, when after the start of therapy was 9 months, Parrish came to Russia together with the head of the Oxford research Foundation in the field of biogerontology, biomedical researcher, scientific consultant of AVI Roy. In the international network of clinics of personalized medicine, a co-founder of which is Dr. Roy, ispytatelniy observed, blood tests, various samples and passes the necessary examinations.

“TRY MY MUSCLES.”

Before the press conference we ran into each other with Elizabeth in the hallway. She immediately thought “KP”, which became the first Russian-language edition published a great candid interview with the researcher. Liz, as a friend, hugged me, told me how she liked it in Moscow – especially the Kremlin and Red square” and then winked: “here’s what I now have muscles” – and held out his hand. Muscles are very dense, solid — these are advanced athletes, but without excessive volume. Liz herself harmonous, tightened.
 Первая женщина, изменившая свои гены, чтобы никогда не стареть

Liz harmonous, tightened, and her muscles – as advanced athletes

Considering the close proximity to her face, I noticed that the skin in perfect condition and hardly touched a light layer of makeup. While Botox, a secret which I suspect Liz skeptics do not smell. On the forehead a pair of shallow wrinkles, which become sharper when she is surprised or emotionally to answer questions. In General, the researcher is in great shape (she’s 45). “Now I don’t have time for classes at the gym — muscles are in a very good, young as exclusively due to the gene therapy,” says Liz.

HOW ARE YOU FEELING?

– I feel fantastic – she smiles at a press conference. We regularly examine my blood, is also soon going to do an MRI, which allows “deep” to view internal organs, body tissue, and including will show changes in the muscles. And in order to reliably determine what age-related changes have happened to me, confirm whether there is rejuvenation, I have tested the full panel of biomarkers — for this purpose we collect information and examine me in the clinic, personalized medicine Dr. Roy. By the way, I’m the first patient to pioneer, which will test biomarkers of aging, is winking to Liz. When this is all clarified, we will publish the data.

– How about skin rejuvenation has changed its status after the start of therapy?

– Samples were taken my skin to the insertion of genetic material, and after, now they will be investigated in the laboratory to determine biological age by methylation (methylation of DNA is one of the scientific methods of determining biological age, today many scholars recognize this analysis is most reliable. – Ed.). And then we find out the truth, ” laughs Liz. And adds: “you Need to keep in mind that I, as the first patient entered the lowest possible dose of genetic material. We did this in order to fulfill the main task — to prove that such treatment is safe and does not cause cancer and effective, that is, an anti-aging changes.

STUDY IN FULL

– How secure is your health? – we are interested in Elizabeth. – Do you take any drugs to support, to reduce the risks?

– No, I do not take any vitamins or anything like that. In addition, for monitoring regularly donate blood every month sometimes twice a month.

“We will also make Liz a number of other studies examine the microbiome (composition and condition of bacteria in the intestine) to find out how it was influenced by changes in the genome, the metabolome (the sum of the products of metabolism) and other data,” adds AVI Roy.

QUESTION-FIN

– Liz, what would you say to skeptics who doubt that you introduced to these genetic constructions, not yet tested on humans? Some even think that it could be just the injection of glucose solution…

– We do full testing of my body, watching the changes, analyze and fix them. The lab of George Church (the American scholar, a leading expert on sequencing the human genome, Professor of genetics at Harvard medical school. – Ed.) sequenced the genes that I introduced — you can test, to verify their presence in the body if necessary. In General, I’m open for research.

But in General, not to trust gene therapy is not a productive approach. Effect on genes — it is not a miracle and not fiction. In the world there is a lot of clinical trials of gene therapy involving human subjects. Yes, I am the first who uses a unique type of gene therapy for anti-aging. But I’m sure soon these patients will become much more.

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