On the clinical implementation of the test too early to say.
The research team from king’s College London (King’s College London) proposed to use to detect depression blood test. This will help to correctly diagnosed, according to the authors, and also to appoint suitable patients antidepressants. Pariante Carmine (Carmine Pariante) and other members of the research team have already experienced they have developed a test for 160 volunteers.
The analysis determined the concentration of two proteins – interleukin-1-beta and factor inhibiting migration of macrophages, which are specific markers of inflammation.
The researchers found that the higher was the concentration of these proteins, the more aggressive therapy required for patients. Indeed, those who had found high concentrations of these inflammatory markers (about one-third of participants), did not respond to therapy with the use of selective inhibitors of serotonin reuptake and tricyclic antidepressants.
The authors believe that these patients should not only prescribe antidepressants, but anti-inflammatory drugs – this will allow you to fight depression is much more efficient. However, to make a decision on the admission of certain drugs, and the changing treatment needs a doctor.
In the near future, the researchers plan to evaluate the effectiveness of the analysis on a larger sample of patients and only then we can speak about clinical implementation of the test.
